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Core Technology

Overview
KineMed's assay technology measures the flow of molecules through complex metabolic pathways and networks in living systems. The technology can be used to gain significant data safely from humans as well as from laboratory animals.


Principles of Technology
KineMed's technology is based on the premise that the operational unit of function in biology is neither the gene nor the protein, but is the flow of molecules through often-complex metabolic pathways. KineMed's tests, called KineMarkers™, measure the flow of molecules through identified pathways responsible for health and disease.

KineMed’s Platform Technology
The proprietary KineMarker™ technology utilizes ultra sensitive mass spectrometry in concert with novel processes for labeling and measuring molecular fluxes in living organisms, including humans. KineMed has extensive intellectual property in molecular kinetics, with five currently issued and a significant number of pending patents. Although the processes and uses of KineMed’s technology are novel and proprietary, the underlying technology involving mass spectrometry is mature.

Comparison to Alternative Laboratory Tests
KineMarkers™ provide a commercially available technology for measuring molecular kinetics. Other laboratory tests, including those from clinical chemistry, immunoassay and genomics/proteomics, provide only static measurements. Molecular kinetics tests differ from static tests in the same way that motion pictures differ from snapshots, by including the dimension of time. New tools are therefore required for measuring the dynamic flow of molecules, just as movie cameras differ from regular snap shot cameras or Polaroid cameras. KineMed's tests provide molecular “motion detectors” and give measurements in terms of rates over time.

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