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Scientific Advisory Board
Marc K. Hellerstein, MD, PhD
Chairman, KineMed
Professor (Calloway Chair), University of California, Berkeley
Professor of Medicine, University of California, San Francisco
Nicholas Chiorazzi, MD
CEO, North Shore-Long Island Jewish Research Institute
Professor of Medicine, New York University School of Medicine
William Evans, PhD
Professor, Donald W. Reynolds Center on Aging
University of Arkansas School of Medicine
Samuel Klein, M.D.
Danforth Professor and Director of the Center for Human Nutrition
Washington University, St. Louis
Dale Johnson, PharmD, PhD
President, Emilien, Inc.
Leonard Makowka, MD, PhD
Co-Founder
Tractus Medical, Inc.
Manoj C. Desai, PhD
Vice President, Medicinal Chemistry
Gilead Sciences, Inc.
Business Advisory Board
Frederick Frank
Vice Chairman
Lehman Brothers
Sally Anne Lynch, PhD
Biotechnology Equity Analyst
General American Investors
Mary Tanner
General Partner
Life Science Partners
Jerry Treppel
General Partner
Wheaton Capital Management
Susan Clymer
Managing Director
Nichi Bei Bio
Biographies of the Scientific Advisory Board
Marc K. Hellerstein, MD, PhD
Chairman, KineMed
Professor (Calloway Chair), University of California, Berkeley
Professor of Medicine, University of California, San Francisco
Dr. Hellerstein joined the faculty of the UC Berkeley in 1987 after completing medical training at Yale Medical School with a fellowship in endocrinology at New England Medical Center and a PhD in nutritional biochemistry from Massachusetts Institute of Technology. Dr. Hellerstein's major research interest has been the measurement of metabolic flux in vivo. By combining powerful technology with novel mathematical approaches and insights into biological systems, his group quantitatively measured many metabolic processes that could not previously be studied. The potential for applications to clinical diagnostics and drug development led directly to the founding of KineMed, Inc. Dr. Hellerstein has advised numerous pharmaceutical companies, including Abbott Laboratories, Entelos, Agouron Pharmaceuticals, Bayer, Genetech, Parke Davis, Pfizer, and Warner Lambert.
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Nicholas Chiorazzi, MD
CEO, North Shore-Long Island Jewish Research Institute
Professor of Medicine, New York University School of Medicine
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William Evans, PhD
Professor, Donald W. Reynolds Center on Aging
University of Arkansas School of Medicine
From 1993 to 1997, Dr. Evans was the director of the Noll Physiological Research Center at the Pennsylvania State University, and from 1982 to 1993, he served as the Chief of the Human Physiology Laboratory at the U.S.D.A. Human Nutrition Research Center on Aging at Tufts University. He is a Fellow of the American College of Sports Medicine, The American College of Nutrition, and an honorary member of the American Dietetic Association. He is the author or co-author of more than 160 publications in scientific journals. His laboratory examines the relationship between exercise, nutrition and aging. His landmark studies have demonstrated the ability of older men and women to improve strength, fitness, and health through exercise, even into the 10th decade of life. He has served as an expert advisor to NASA in a number of committees, including the Science Working Group responsible for the design of the Human Research Facility aboard the International Space Station and The Life Sciences Advisory Subcommittee. He also served at the head of the Nutrition and Exercise research group for the National Space Biomedical Institute.
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Samuel Klein, MD
Danforth Professor and Director
Center for Human Nutrition
Washington University
Dr. Klein is the director of the Washington University Center for Human Nutrition, associate program director of the General Clinical Research Center, and medical director of the Barnes-Jewish Hospital Nutrition Support Service. He is also a professor of medicine at Washington University School of Medicine in St. Louis. He received his MD from Temple University Medical School, and an MS in nutritional biochemistry and metabolism from the Massachusetts Institute of Technology. He completed his residency training in internal medicine and a clinical nutrition fellowship at University Hospital in Boston. He also completed a nutrition research fellowship at Harvard Medical School in Boston and a gastroenterology fellowship at the Mount Sinai Hospital in New York. Dr. Klein's primary research is focused on the regulation of metabolism, particularly lipid metabolism in obesity.
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Dale Johnson, PharmD, PhD
President, Emilien, Inc.
Dr. Johnson is a founder and president and CEO of Emiliem, Inc., a biotechnology company in the San Francisco Bay Area that focuses on creating new oncology therapeutics. He has over 25 years of experience in biotechnology and pharmaceutical research and development activities, in which he has led and managed groups ranging from small units in start-up companies to multinational units in large corporations. Dr. Johnson has participated in the research and development of over 100 compounds of which 15 have become marketed healthcare medicinal products in the United States and Europe. Most recently, he served as vice president, drug assessment & cevelopment at Chiron Corporation and previously as vice president, preclinical development. Prior research and development positions include Hoechst-Roussel Pharmaceuticals, Inc., International Research and Development Corp. (a preclinical CRO), Lederle (American Cyanamid), and Eos Biotechnology. Dr. Johnson received his PhD in toxicology from the University of Michigan where he was awarded an AFPE Fellowship. Before his PhD studies, he received a BS and a PharmD from the University of Michigan and completed a clinical pharmacy residency at UM Medical Center where he was awarded the National Resident of the Year Award. He is a diplomate of the American Board of Toxicology and serves as a member of industry and government advisory boards. Dr. Johnson is co-editor of the journals The Chemistry of Metabolic and Toxicological Processes and Current Opinion in Drug Discovery & Development and is an adjunct professor in molecular toxicology at University of California, Berkeley, where he teaches computational toxicology.
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Leonard Makowka, MD, PhD
Co-Founder
Tractus Medical, Inc.
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Manoj C. Desai, PhD
Vice President, Medicinal Chemistry
Gilead Sciences, Inc.
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Business Advisory Board
Frederick Frank
Vice Chairman
Lehman Brothers
Mr. Frank attended received his MBA from Stanford in 1958 and began his Wall Street career. Frederick Frank is vice chairman and a director of Lehman Brothers, Inc. Before joining Lehman Brothers as a partner in October, 1969, he was co-director of research, as well as vice president and director, of Smith, Barney & Co. Inc. He is a chartered financial analyst, a member of The New York Society of Security Analysts and a past president of the Chemical Processing Industry Analysts. Mr. Frank graduated from the Hotchkiss School in 1950 and from Yale University in 1954. He then spent two years in the Army, most of the time stationed with Supreme Headquarters Allied Powers Europe (SHAPE) in Paris. In addition to serving as a director of business engine, Diagnostic Products Corporation, Digital Arts & Sciences, Inc., eSoft, Incorporated, Landec Corporation, Pharmaceutical Product Development, Inc., and Predix Pharmaceuticals, he is chairman of the National Genetics Foundation, a director of the Salk Institute, former president of the board and currently trustee emeritus of The Hotchkiss School, a member of the Yale School of Organization and Management Advisory Board, a member of the Pharmaceutical Executive Magazine advisory board, a member of the Board of Governors of the National Center for Genome Resources, Chairman of the Board of The Irvington Institute for Immunological Research, a Director of the Institute for Systems Biology and an Advisory Board Member of The Johns Hopkins Bloomberg School of Public Health, a member of the Dean's Council of The Harvard School of Public Health, and an Advisory Board Member of the MIT Center for BioMedical Innovation. Mr. Frank has provided investment banking services to a host of companies in the pharmaceutical, biotechnology, healthcare service providers, medical device nutraceutical, and high technology industries. He has been involved in hundreds of financings and merger and acquisition transactions in the health care field.
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Sally Anne Lynch, PhD
PhD
Biotechnology Equity Analyst
General American Investors
Dr. Lynch is a biotechnology equity analyst at General American Investors, a publicly traded closed end mutual fund with assets of $1.2 billion. Approximately 10% of the fund is under Dr. Lynch's management. Dr. Lynch received her PhD in molecular biology from the State University of New York at Stony Brook in 1988 and was a postdoctoral research fellow at Memorial Sloan Kettering Cancer Center, Division of Solid Tumor Immunology from 1988 to 1994.
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Mary Tanner
General Partner
Life Science Partners
Ms. Tanner is founder and Managing Director of Life Sciences Partners, a healthcare investment and advisory firm. From 2001 to 2004, she was senior managing director at Bear, Stearns & Co., Inc., a financial services company. Before Bear, Stearns, Ms. Tanner was a healthcare consultant from 2000 to 2001 and held various positions at Lehman Brothers Inc., a financial services company, including managing director and head of the health care practice, from 1984 to 2000. She was the first woman managing director at Lehman Brothers. Ms. Tanner received her BA from Harvard.
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Jerry Treppel
General Partner
Wheaton Capital Management
Mr. Treppel is the general partner of Wheaton HealthCare Partners LP. His previous position was a managing director at Banc America Securities. For the past 15 years, he has analyzed the area of specialty pharmaceuticals and created the first investor conference in the sector. Mr. Treppel has been widely recognized for his expertise in this area, accruing accolades from Reuters, Institutional Investor, and the Wall Street Journal for his excellence in industry knowledge.
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Susan Clymer
Managing Director
Nichi Bei Bio
Ms. Clymer is the Managing Director and founder of NichiBei Bio, Inc. Ms. Clymer has extensive biopharma business development and deal making experience from more than 25 years of business experience in the U.S. and Japanese biotechnology industries, has overseen multiple M&A deals, and has served on the Board of Directors of several private and public biotechnology companies including Sapient Health Network (acquired by WebMD in 2000), Goulter Medical, and TransMedx. She is currently a Board member of ReqMed, a Japanese life science venture company and Osprey Pharmaceutical, a Canadian bioventure company located in Montreal.
Prior to founding Nichi Bei Bio, Ms. Clymer was a Fulbright Scholar in Japan affiliated with the Japan Bioindustry Association (JBA) created by the Ministry of International Trade and Industry and Tokyo University. From 1984 - 1989, Ms. Clymer worked in business development at Scios (formerly California Biotechnology) and Bio-Response (acquired by Baxter Healthcare). From 1978 - 1984 she was an analyst with the U.S. Congressional Office of Technology Assessment (OTA) where she co-authored an in-depth report for Congressman Albert Gore Jr. on Japan's competitive position in biotechnology.
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